Cooling Agent WS-5 Powder

Cooling Agent WS-5 Powder

What is Cooling Agent WS-5 Powder?

TIZAN Cooling Agent WS-5 Powder [Ethyl 3-(p-menthane-3-carboxamido)acetate], CAS No. 68489-14-5, FEMA 4309. It is the latest in a long line of cooling agents. Each have their own different ways of cooling different areas of the mouth and tongue and to different degrees. It is one of the strongest of all the cooling agents and is derived from menthol, although it is virtually odorless and has no taste. It provides a smooth and well rounded cooling effect and primarily affects the roof of the mouth and the back of the tongue.

The neoisomers of WS-5 and menthyl lactate showed higher cooling potency over the l-isomers. Where the neoisomer did not show higher cooling potency such as with WS-3, blending of the two isomers may still be advantageous in providing a better in-use experience, such as was demonstrated with the G-180 and neo-G-180 blend, wherein the negative sensory effects from using G-180 alone was modulated by the neoisomer. The neo-derivatives of menthyl lactate showed surprising cooling power. In particular, neo-menthyl lactate (2S) and neo-menthyl lactate acetate [(1S,2S,5R)-2-isopropyl-5-methylcyclohexyl-2(S)-acetoxypropanoate] provided very strong initial cooling as well as over the 60 minute time period, compared to l-menthyl lactate.

TIZAN Cooling Agent WS-5 Powder Chemical & Physical Properties

CAS No.68489-14-5
Density1.0±0.1 g/cm3
Boiling Point390.9±11.0 °C at 760 mmHg
Molecular FormulaC15H27NO3
Molecular Weight269.380
Flash Point190.2±19.3 °C
Exact Mass269.199097
Vapour Pressure0.0±0.9 mmHg at 25°C
Index of Refraction1.462

Glycine, N-[[5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, ethyl ester

Ethyl 2-(((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)amino)acetate

FEMA No. 4309


N-((Ethoxycarbonyl)methyl)-p-menthane-3-carboxamide [FIFH]

Ethyl N-[(2-isopropyl-5-methylcyclohexyl)carbonyl]glycinate

Glycine,N-((5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl)-,ethyl ester,(1R-(1alpha,2beta,5alpha))

Glycine,N-(((1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl)-,ethyl ester

TIZAN Cooling Agent WS-5 Powder Application

  1. Applied in daily flavor.
  2. Applied in food flavor.
  3. Applied in industrial flavor.
  4. Applied in tobacco flavor.

Best Cooling Agent WS-5 Powder

Tizan enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our product, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our product on-time.

We also focus on value-added services. We are available for service questions and information to support your business.

Why Choose TIZAN Cooling Agent WS-5 Powder?

Tizan specialize in Cooling Agent WS-5 Powder [Ethyl 3-(p-menthane-3-carboxamido)acetate] for several years, we supply product with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.

Where to buy Cooling Agent WS-5 Powder?

Just send email to [email protected], or submit your requirement in bottom form, we are of service at any time


WS-5 Powder is light sensitive, the solid material and any solutions obtained are protected from exposure to light.

  • 25Kg/Fiber Drum, double plastic bag inside, with carton outside.
  • Sample – aluminum foil bag vacuum packing.

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