What is Ursolic acid (Rosemary extract powder)?
Ursolic acid (Rosemary extract powder) is a pentacyclic triterpenoid identified in the epicuticular waxes of apples as early as 1920 and widely found in the peels of fruits, as well as in herbs and spices like rosemary and thyme. It is a cosmetics additive, and it can serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents.
What is Rosemary Extract?
Rosemary extract is a series natural plant extracts which extracted from Rosmarinus officinalis L, also named rosemary leaf extract. Applied to the skin, rosemary essential oil helps strengthen the capillaries and has a rejuvenating effect. Recent research is now revealing even more benefits attached to this remarkable herb, including its ability to help prevent cancer and age-related skin damage, boost the functioning of the liver and act as a mild diuretic to help reduce swelling. Although rosemary extract has been used commercially as an antimicrobial food preservative for years, now we know for certain that it also has a lot to offer as a nutritional supplement, 1 especially in the prevention of some types of cancer, allergies, and the progression of Alzheimer’s disease.
Rosmarinic acid exhibits various pharmacological activities including prevention of oxidation of low density lipoprotein, inhibition of murine cell proliferative activity and of cyclooxygenase, and anti-allergic action.
Ursolic aicd has wide biological effect and antioxidant effect, which act positively in anti-aging and removing splash. It can prevent and improve wrinkle and old-age splash through restore the skin’s collagen bundle construction and elastic. As a kind of cosmetics, it’s steady, its color and odor won’t change with the time. In addition, it has a good sense of touch.
Carnosic acid has outstanding fat-solubility, which can be used as antioxidant in meat, dairy products, oily-rich products, sweets.
Carnosol is a major component of Rosmarinus officinalis, it is a phenolic diterpene that has potent antioxidant and anti-inflammatory activities.
Ursolic acid benefits
It is well known to possess a wide range of biological functions, such as antioxidative, anti-inflammatory, antihyperlipidemic and anticancer activities, that are able to counteract endogenous and exogenous biological stimuli.
It was shown to stimulate muscle growth, provide a cardioprotective effect, and reduce the risk of obesity.
Ursolic acid is effective in protecting against chemically induced liver injury in laboratory animals. The mechanism of hepatoprotection by these two compounds may involve the inhibition of toxicant activation and the enhancement of the body defense systems.
Ursolic acid has been noted for their antitumor-promotion activities. Ursolic acid is capable of inducing apoptosis in tumor cells on one side and to prevent malignant transformation of normal cells on the other side. It also interferes with numerous enzymes, including the ones serving directly to DNA synthesis.
Ursolic acid induced apoptosis via inhibition of NF-kappaB induced bcl-2 mediated anti-apoptotic pathway and subsequent activation of p53 mediated and TNF-alpha induced caspase-3 mediated pro-apoptotic pathways in a study of B16F-10 melanoma cells.
In contrast to these beneficial properties, some laboratory studies have recently revealed that the side effects of ursolic acid on normal cells and tissues are occasionally pro-inflammatory. Otherwise, ursolic acid is relatively non-toxic, and has been used in cosmetics and health products.
Ursolic acid (Rosemary extract powder) Specification
|Latin Name||Rosmarinus officinalis L.|
|Part of Used||Leaf|
|Active Ingredients||Ursolic Acid|
|Specification Available||Ursolic Acid 5%, 10%,15%, 20%,25%,30%, 50%, 90% HPLC|
|Appearance||Yellow Greenish to Light Yellow Powder or White Powder|
Store in tightly sealed containers in cool and dry place, away from moisture, light, oxygen.
- Packed in paper-drums and two plastic-bags inside. N.W:25kgs .I.D.35×H51cm.
- 1Kg/Bag, aluminum foil bag vacuum packing.
- Sample, double sealed water plastic bags inside with the aluminum bag outside.
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